Novel pattern recognition methods for classification and detection in remote sensing and power generation applications

Novel pattern recognition methods for classification and detection in remote sensing and power generation application

experimental evaluation of artificial defects using smart thermography

Abstract SMArt termography is an innovative and promising technique that could be useful for the detection of damages of large components subjected to in-service loads, like wind blade. This technique requires building traditional carbon or glass fiber reinforced composite laminates adding a regular net of Shape Memory Alloy (SMA) wires in the matrix. These wires confer to the composite material additional features. In particular, the electro-thermal properties of SMA could be used as an internal heat source to be used for the control of the component using the traditional numerical technique used to elaborate the raw thermal data. Despite of other thermography techniques, SMArt thermography is characterized by a quite reduced amount of heating power, which produces a limited increasing of the temperature of the component subjected to control. On the other hand, the numerical elaboration of thermal data acquired from IR camera is more sensitive and require a deeper comprehension of the phenomena. In this work, a GFRP composite panel containing several artificial defects has been studied both from a numerical and experimental point of view, in order to determine the sensitivity of the technique, the limit of applicability and practical indications about the reliability of the technique

Numerical and experimental validation of SMArt thermography for the inspection of wind blade composite laminate

none3noAn innovative active thermography technique is proposed for the inspection of typical wind blade material. The proposed technique is based on the use of a multifunctional material obtained adding a grid of Shape Memory Alloy wires, which would serve also as a protection against lightning, to a traditional glass fibre composite panel. This technique, called SMArt thermography, which exploits the SMA wires as internal heat sources, has been compared to a traditional pulsed thermography in the case of a representative panel of unidirectional glass fibre and epoxy matrix with embedded SMA wires and artificial defects. The experimental results of the two techniques are reported and compared to the result of a numerical FEM transient model, in order to establish the reliability and the detectability limit of the proposed technique. The FEM model has been proven to be a useful tool for the definition of the multifunctional material at a design stage.openMarta De Giorgi; Riccardo Nobile; Andrea SaponaroDE GIORGI, Marta; Nobile, Riccardo; Saponaro, Andre

Experimental evaluation of artificial defects using SMArt thermography

SMArt termography is an innovative and promising technique that could be useful for the detection of damages of large components subjected to in-service loads, like wind blade. This technique requires building traditional carbon or glass fiber reinforced composite laminates adding a regular net of Shape Memory Alloy (SMA) wires in the matrix. These wires confer to the composite material additional features. In particular, the electro-thermal properties of SMA could be used as an internal heat source to be used for the control of the component using the traditional numerical technique used to elaborate the raw thermal data. Despite of other thermography techniques, SMArt thermography is characterized by a quite reduced amount of heating power, which produces a limited increasing of the temperature of the component subjected to control. On the other hand, the numerical elaboration of thermal data acquired from IR camera is more sensitive and require a deeper comprehension of the phenomena. In this work, a GFRP composite panel containing several artificial defects has been studied both from a numerical and experimental point of view, in order to determine the sensitivity of the technique, the limit of applicability and practical indications about the reliability of the technique

Identification of murine phosphodiesterase 5A isoforms and their functional characterization in HL-1 cardiac cell line

Phosphodiesterase 5A (PDE5A) specifically degrades the ubiquitous second messenger cGMP and experimental and clinical data highlight its important role in cardiac diseases. To address PDE5A role in cardiac physiology, three splice variants of the PDE5A were cloned for the first time from mouse cDNA library (mPde5a1, mPde5a2 and mPde5a3). The predicted amino acidic sequences of the three murine isoforms are different in the N-terminal regulatory domain. mPDE5A isoforms were transfected in HEK293T cells and they showed high affinity for cGMP and similar sensitivity to sildenafil inhibition. RT-PCR analysis showed that mPde5a1, mPde5a2 and mPde5a3 had differential tissue distribution. In the adult heart, mPde5a1 and mPde5a2 were expressed at different levels whereas mPde5a3 was undetectable. Overexpression of mPDE5As induced an increase of HL-1 number cells which progress into cell cycle. mPDE5A1 and mPDE5A3 overexpression increased the number of polyploid and binucleated cells, mPDE5A3 widened HL-1 areas and modulated hypertrophic markers more efficiently respect to the other mPDE5A isoforms. Moreover, mPDE5A isoforms had differential subcellular localization: mPDE5A1 was mainly localized in the cytoplasm, mPDE5A2 and mPDE5A3 were also nuclear localized. These results demonstrate for the first time the existence of three PDE5A isoforms in mouse and highlight their potential role in the induction of hypertrophy. This article is protected by copyright. All rights reserved

Sub-50-nm conjugated polymer dots by nanoprinting.

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Balneotherapy for osteoarthritis: a systematic review

: This systematic review is aimed to evaluate the effects of balneotherapy with thermal mineral water for managing the symptoms and signs of osteoarthritis located at any anatomical site. The systematic review was conducted according to the PRISMA Statement. The following databases were consulted: PubMed, Scopus, Web of Science, Cochrane Library, DOAJ and PEDro. We included clinical trials evaluating the effects of balneotherapy as a treatment for patients with osteoarthritis, published in English and Italian language, led on human subjects. The protocol was registered in PROSPERO. Overall, 17 studies have been included in the review. All of these studies were performed on adults or elderly patients suffering from osteoarthritis localized to knees, hips, hands or lumbar spine. The treatment assessed was always the balneotherapy with thermal mineral water. The outcomes evaluated were pain, palpation/pressure sensibility, articular tenderness, functional ability, quality of life, mobility, deambulation, ability to climb stairs, medical objective and patients' subjective evaluation, superoxide dismutase enzyme activity, serum levels of interleukin-2 receptors. The results of all the included studies agree and demonstrated an improvement of all the symptoms and signs investigated. In particular, pain and quality of life were the main symptoms evaluated and both improved after the treatment with thermal water in all the studies included in the review. These effects can be attributed to physical and chemical-physical properties of thermal mineral water used. However, the quality of many studies resulted not so high due and, consequently, it is necessary to perform new clinical trial in this field using more correct methods for conducting the study and for processing statistical data

Alexithymia, anger and psychological distress in patients with myofascial pain: a case-control study

Aims: The aim of this study was to investigate psychological distress, anger and alexithymia in a group of patients affected by myofascial pain (MP) in the facial region. Methods: 45 MP patients [mean (SD) age: 38.9 (11.6)] and 45 female healthy controls [mean (SD) age: 37.8 (13.7)] were assessed medically and psychologically. The medically evaluation consisted of muscle palpation of the pericranial and cervical muscles. The psychological evaluation included the assessment of depression (Beck Depression Inventory—short form), anxiety [State-Trait Anxiety Inventory Form Y (STAI-Y)], emotional distress [Distress Thermometer (DT)], anger [State-Trait Anger Expression Inventory—2 (STAXI-2)], and alexithymia [Toronto Alexithymia Scale (TAS)]. Results: the MP patients showed significantly higher scores in the depression, anxiety and emotional distress inventories. With regard to anger, only the Anger Expression-In scale showed a significant difference between the groups, with higher scores for the MP patients. In addition, the MP patients showed significantly higher alexithymic scores, in particular in the Difficulty in identifying feelings (F1) subscale of the TAS-20. Alexithymia was positively correlated with the Anger Expression-In scale. Both anger and alexithymia showed significant positive correlations with anxiety scores, but only anger was positively correlated with depression. Conclusion: A higher prevalence of depressive and anxiety symptoms associated with a higher prevalence of alexithymia and expression-in modality to cope with anger was found in the MP patients. Because the presence of such psychological aspects could contribute to generate or exacerbate the suffering of these patients, our results highlight the need to include accurate investigation of psychological aspects in MP patients in normal clinical practice in order to allow clinicians to carry out more efficacious management and treatment strategies

Advanced CMR Techniques in Anderson-Fabry Disease: State of the Art

Anderson-Fabry disease (AFD) is a rare multisystem X-linked lysosomal storage disorder caused by α-galactosidase A enzyme deficiency. Long-term cardiac involvement in AFD results in left ventricular hypertrophy and myocardial fibrosis, inducing several complications, mainly arrhythmias, valvular dysfunction, and coronary artery disease. Cardiac magnetic resonance (CMR) represents the predominant noninvasive imaging modality for the assessment of cardiac involvement in the AFD, being able to comprehensively assess cardiac regional anatomy, ventricular function as well as to provide tissue characterization. This review aims to explore the role of the most advanced CMR techniques, such as myocardial strain, T1 and T2 mapping, perfusion and hybrid imaging, as diagnostic and prognostic biomarkers